Masai Mara Game Reserve (Kenya)
Serengeti National Park (Tanzania)
Etosha National Park (Namibia)
Chobe National Park (Botswana)
Kruger National Park (South Africa)
Mole National Park (Ghana)
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I can personally recommend Kruger NP, Chobe, Etosha and Masia Mara. I hear that the Serengeti is great as well. Not sure about Mole.
You will enjoy a safari especially in Botswana, Kenya and South Africa. [...]